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Index of Diseases
R
Rabies
Definition: An acute infectious disease of the central nervous system affecting almost all mammals, including humans. It is caused by a rhabdovirus and usually spread by contamination with virus-laden saliva of bites inflicted by rabid animals. Important animal vectors include the dog, cat, vampire bat, mongoose, skunk, wolf, raccoon, and fox. (From Dorland, 27th ed) Annotation: caused by a rhabdovirus; human & animal ID#: D011818Radial Neuropathy
Definition: Disease involving the RADIAL NERVE. Clinical features include weakness of elbow extension, elbow flexion, supination of the forearm, wrist and finger extension, and thumb abduction. Sensation may be impaired over regions of the dorsal forearm. Common sites of compression or traumatic injury include the AXILLA and radial groove of the HUMERUS. Annotation: ID#: D020425Radiation Pneumonitis
Definition: Injurious effects of radiotherapy on the lungs. There are three phases in the reaction of the lungs to radiation injury: an acute phase occurring 1 to 2 months after exposure, a subacute phase 2 to 9 months after exposure, and a chronic or fibrotic phase more than 9 months after exposure. In the acute phase there is vascular damage, congestion, edema, and mononuclear cell infiltration; in the subacute phase the alveolar walls are infiltrated with mononuclear inflammatory cells and fibroblasts; in the chronic phase, alveolar fibrosis and capillary sclerosis take place. (Cecil Textbook of Medicine, 19th ed, p2343) Annotation: an interstitial lung dis; assume to be caused by radiother so do not coord routinely with RADIOTHERAPY /adv eff; coord IM with other type or source of radiation with /adv eff (IM) if pertinent; DF: RAD PNEUMONITIS ID#: D017564Radicular Cyst
Definition: Slow-growing fluid-filled epithelial sac at the apex of a tooth with a nonvital pulp or defective root canal filling. Annotation: non-neoplastic periodontal cyst; /blood supply /chem /secret /ultrastruct permitted; coord IM with organ/dis (IM), not organ/neopl ID#: D011842Radiculopathy
Definition: Disease involving a spinal nerve root (see SPINAL NERVE ROOTS) which may result from compression related to INTERVERTEBRAL DISK DISPLACEMENT; SPINAL CORD INJURIES; SPINAL DISEASES; and other conditions. Clinical manifestations include radicular pain, weakness, and sensory loss referable to structures innervated by the involved nerve root. Annotation: disease of a single spinal nerve root; do not confuse with POLYRADICULOPATHY (dis of several spinal nerve roots) nor with POLYRADICULONEUROPATHY (dis of both spinal nerve roots & peripheral nerves) ID#: D011843Radiodermatitis
Definition: A cutaneous inflammatory reaction occurring as a result of exposure to ionizing radiation. Annotation: from ionizing radiation ID#: D011855Radius Fractures
Definition: Annotation: ID#: D011885Ranula
Definition: A form of retention cyst of the floor of the mouth, usually due to obstruction of the ducts of the submaxillary or sublingual glands, presenting a slowly enlarging painless deep burrowing mucocele of one side of the mouth. It is also called sublingual cyst and sublingual ptyalocele. Annotation: non-neoplastic; /blood supply /chem /secret /ultrastruct permitted ID#: D011900Rat-Bite Fever
Definition: A syndrome characterized by recurring fever, rash, and arthralgias occurring days to weeks after a rat bite. The causative agents are either Streptobacillus moniliformis or Spirillum minus. Annotation: a disease entity caused by a gram-neg bact ID#: D011906Raynaud's Disease
Definition: An idiopathic vascular disorder characterized by bilateral attacks of Raynaud's phenomenon. It affects females more often than males. (From Dorland, 27th ed) Annotation: idiopathic vasc disord ID#: D011928Rectal Diseases
Definition: Annotation: inflamm dis = PROCTITIS ID#: D012002Rectal Fistula
Definition: Abnormal passage communicating with the rectum. Annotation: fistula policy: Manual 23.19+; do not confuse X ref ANAL FISTULA with FISSURE IN ANO; RECTOVAGINAL FISTULA is also available ID#: D012003Rectal Neoplasms
Definition: Tumors or cancer of the RECTUM. Annotation: coord IM with histol type of neopl (IM); familial: consider also COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS ID#: D012004Rectal Prolapse
Definition: Protrusion of the rectal mucous membrane through the anus. There are various degrees: incomplete with no displacement of the anal sphincter muscle; complete with displacement of the anal sphincter muscle; complete with no displacement of the anal sphincter muscle but with herniation of the bowel; and internal complete with rectosigmoid or upper rectum intussusception into the lower rectum. Annotation: ID#: D012005Rectocele
Definition: A hernial protrusion of part of the rectum into the vagina. (Dorland, 28th ed) Annotation: ID#: D020047Rectovaginal Fistula
Definition: Abnormal communication between the rectum and the vagina. Annotation: fistula policy: Manual 23.19+ ID#: D012006Recurrence
Definition: The return of a sign, symptom, or disease after a remission. Annotation: never IM; /prev permitted: coord NIM with disease /prev (IM) ID#: D012008Red-Cell Aplasia, Pure
Definition: Suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production. Annotation: a form of anemia ID#: D012010Reflex Sympathetic Dystrophy
Definition: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33) Annotation: DF: CRPS TYPE I ID#: D012019Refractive Errors
Definition: Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus. Annotation: deviations from standard refraction of eye; DF: REFRACTIVE ERR ID#: D012030Refsum Disease
Definition: An autosomal recessive familial disorder that usually presents in childhood with POLYNEUROPATHY, sensorineural DEAFNESS; ICHTHYOSIS; ATAXIA; RETINITIS PIGMENTOSA; and cardiomyopathy. CEREBROSPINAL FLUID PROTEINS and serum PHYTANIC ACID are generally elevated. This condition is associated with the impaired metabolism of phytanic acid in PEROXISOMES. (From Joynt, Clinical Neurology, 1991, Ch37, p58-9; Rev Med Interne 1996;17(5):391-8) Annotation: do not confuse with REFSUM DISEASE, INFANTILE see PEROXISOMAL DISORDERS ID#: D012035Reiter Disease
Definition: A triad of nongonococcal urethritis followed by conjunctivitis and arthritis, of unknown etiology. Annotation: ID#: D012058Relapsing Fever
Definition: An acute infection characterized by recurrent episodes of pyrexia alternating with asymptomatic intervals of apparent recovery. This condition is caused by spirochetes of the genus BORRELIA. It is transmitted by the bites of either the body louse (PEDICULUS humanus corporis), for which humans are the reservoir, or by soft ticks of the genus ORNITHODOROS, for which rodents and other animals are the principal reservoirs. Annotation: not for "recurrent fever" ( = FEVER (IM) + RECURRENCE (NIM) ) ID#: D012061Renal Artery Obstruction
Definition: Narrowing or occlusion of the renal arteries. It is due usually to atherosclerosis, fibromuscular dysplasia, thrombosis, embolism, or external pressure. It may result in renovascular hypertension. Annotation: obstruct of external or internal origin; renal artery thrombosis: coord IM with THROMBOSIS (IM); consider also HYPERTENSION, RENOVASCULAR (hypertension caused by renal artery obstruct or compress) ID#: D012078Renal Osteodystrophy
Definition: Decalcification of bone due to hyperparathyroidism secondary to chronic kidney disease. Annotation: ID#: D012080Renal Tubular Transport, Inborn Errors
Definition: Genetically determined disorders of the reabsorptive functions of the kidney with regard to specific nephron segments responsible for specific transport functions, classifiable by proximal nephron function, loop of Henle function, and distal nephron function. The transport defects can be selective or nonselective. (From Cecil Textbook of Medicine, 19th ed, p584; Harrison's Principles of Internal Medicine, 12th ed, p1140) Annotation: GEN or unspecified; prefer specific; coord IM with specific metabolite /metab (IM); do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; DF: RENAL TUB TRANSP INBORN ERR ID#: D015499Reoviridae Infections
Definition: Infections produced by reoviruses, general or unspecified. Annotation: GEN or unspecified; prefer specific ID#: D012088Reperfusion Injury
Definition: Functional, metabolic, or structural changes, including necrosis, in ischemic tissues thought to result from REPERFUSION to ischemic areas of the tissue. The most common instance is MYOCARDIAL REPERFUSION INJURY. Annotation: ID#: D015427Respiration Disorders
Definition: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available. Annotation: GEN or unspecified; prefer specifics ID#: D012120Respiratory Distress Syndrome
Definition: A condition of the newborn marked by dyspnea with cyanosis, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause. (From Dorland, 27th ed) Annotation: infants only; for adults use RESPIRATORY DISTRESS SYNDROME, ADULT; do not confuse with "respiratory distress" which may be RESPIRATORY INSUFFICIENCY or a specific; do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; check tags HUMAN & INFANT, NEWBORN ID#: D012127Respiratory Distress Syndrome, Adult
Definition: A syndrome of life-threatening progressive pulmonary insufficiency in the absence of known pulmonary disease, usually following a systemic insult such as surgery or major trauma. Annotation: RESPIRATORY DISTRESS SYNDROME is for infants DF: note short X refs ID#: D012128Respiratory Hypersensitivity
Definition: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and HAY FEVER. Annotation: "respiratory allergy" ID#: D012130Respiratory Insufficiency
Definition: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) Annotation: do not confuse with RESPIRATORY DISTRESS SYNDROME in newborn inf ID#: D012131Respiratory Paralysis
Definition: Complete or severe weakness of the muscles of respiration. This condition may be associated with MOTOR NEURON DISEASES; PERIPHERAL NERVE DISORDERS; NEUROMUSCULAR JUNCTION DISEASES; SPINAL CORD DISEASES; injury to the PHRENIC NERVE; and other disorders. Annotation: ID#: D012133Respiratory Syncytial Virus Infections
Definition: Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported. Annotation: caused by a pneumovirus ID#: D018357Respiratory System Abnormalities
Definition: Congenital structural abnormalities of the respiratory system. Annotation: for congen struct abnorm only; GEN or unspecified; prefer specifics or specific organ /abnorm; do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; DF: RESPIRATORY SYSTEM ABNORM ID#: D015619Respiratory Tract Diseases
Definition: Annotation: GEN or unspecified; prefer specifics; /diag: consider also DIAGNOSTIC TECHNIQUES, RESPIRATORY SYSTEM; DF: RESPIRATORY TRACT DIS ID#: D012140Respiratory Tract Fistula
Definition: An abnormal passage communicating between any component of the respiratory tract or between any part of the respiratory system and surrounding organs. Annotation: GEN or unspecified; prefer specifics; fistula policy: Manual 23.19+ ID#: D016156Respiratory Tract Infections
Definition: Annotation: GEN: prefer specifics; DF: RESPIRATORY TRACT INFECT ID#: D012141Respiratory Tract Neoplasms
Definition: Annotation: GEN: prefer specific precoord; /blood supply /chem /second /secret /ultrastruct permitted; coord IM with histol type of neopl (IM) ID#: D012142Respirovirus Infections
Definition: Infections with viruses of the genus RESPIROVIRUS, family PARAMYXOVIRIDAE. Host cell infection occurs by adsorption, via hemagglutinin, to the cell surface. Annotation: GEN or unspecified; prefer specifics ID#: D010253Reticuloendotheliosis
Definition: Hyperplasia of reticuloendothelial tissue, in any organ or tissue. A related concept is reticulosis which is an increase in reticuloendothelial elements. Annotation: neoplastic; do not use /blood supply /chem /second /secret /ultrastruct; coord IM with precoord organ/neopl term (IM) ID#: D012158Retinal Artery Occlusion
Definition: Occlusion or closure of the central retinal artery causing sudden, usually nearly complete, loss of vision in one eye. Occlusion of the branch retinal artery causes sudden visual loss in only a portion of the visual field. Annotation: ID#: D015356Retinal Degeneration
Definition: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304) Annotation: retinal dystrophy or macular dystrophy: index under RETINAL DEGENERATION or MACULAR DEGENERATION relying on text & refs ID#: D012162Retinal Detachment
Definition: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12). Annotation: /surg: consider also SCLERAL BUCKLING; X ref RETINAL PIGMENT EPITHELIAL DETACHMENT: do not coord with PIGMENT EPITHELIUM OF EYE unless particularly discussed ID#: D012163Retinal Diseases
Definition: Annotation: inflamm dis = RETINITIS or CHORIORETINITIS; retinal dystrophy: index under RETINAL DEGENERATION or MACULAR DEGENERATION relying on text & refs ID#: D012164Retinal Drusen
Definition: Colloid or hyaline bodies lying beneath the retinal pigment epithelium. They may occur either secondary to changes in the choroid that affect the pigment epithelium or as an autosomal dominant disorder of the retinal pigment epithelium. Annotation: colloid or hyalin bodies under retinal pigment; do not confuse with OPTIC DISK DRUSEN, hyalin bodies in optic nerve ID#: D015593Retinal Dysplasia
Definition: Congenital, often bilateral, retinal abnormality characterized by the arrangement of outer nuclear retinal cells in a palisading or radiating pattern surrounding a central ocular space. This disorder is sometimes hereditary. Annotation: do not use /congen & do not coord with INFANT, NEWBORN, DISEASES ID#: D015792Retinal Hemorrhage
Definition: Bleeding from the vessels of the retina. Annotation: ID#: D012166Retinal Necrosis Syndrome, Acute
Definition: Mild to fulminant necrotizing vaso-occlusive retinitis associated with a high incidence of retinal detachment and poor vision outcome. Annotation: a form of retinitis; DF: ARN SYNDROME ID#: D015882Retinal Neoplasms
Definition: Tumors or cancer of the RETINA. Annotation: /blood supply /chem /second /secret /ultrastruct permitted; coord IM with histol type of neopl (IM) but majority will be RETINOBLASTOMA (see note there) ID#: D019572Retinal Neovascularization
Definition: Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina. Annotation: ID#: D015861Retinal Perforations
Definition: Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes. Annotation: ID#: D012167Retinal Vein Occlusion
Definition: Occlusion of the retinal vein. Those at high risk for this condition include patients with hypertension, diabetes mellitus, arteriosclerosis, and other cardiovascular diseases. Annotation: ID#: D012170Retinitis
Definition: Inflammation of the RETINA. It is rarely limited to the retina, but is commonly associated with diseases of the choroid (CHORIORETINITIS) and of the OPTIC DISK (neuroretinitis). Annotation: ID#: D012173Retinitis Pigmentosa
Definition: Hereditary, progressive degeneration of the neuroepithelium of the retina characterized by night blindness and progressive contraction of the visual field. Annotation: ID#: D012174Retinoblastoma
Definition: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104) Annotation: /blood supply /chem /second /secret /ultrastruct permitted; coord IM with RETINAL NEOPLASMS (IM); /genetics: consider also GENES, RETINOBLASTOMA ID#: D012175Retinopathy of Prematurity
Definition: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed) Annotation: do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; caused by oxygen ther of premature inf but for this etiol, do not use /chem ind: use /etiol if this etiol is discussed at all (& then probably NIM): TN 167 ID#: D012178Retrobulbar Hemorrhage
Definition: Hemorrhage within the orbital cavity, posterior to the eyeball. Annotation: do not confuse with EYE HEMORRHAGE or its specifics, hemorrh of eye tissue ID#: D019315Retrocochlear Diseases
Definition: Diseases of the VESTIBULOCOCHLEAR NERVE. Retrocochlear refers to the eighth cranial nerve and cerebellopontine angle as opposed to the cochlea. (Dorland, 28th ed) Annotation: "retrocochlear" refers to the vestibulocochlear nerve, not the cochlea; GEN or unspecified; prefer specifics; DF: RETROCOCHLEAR DIS ID#: D012181Retrognathism
Definition: Retrusion of the mandible. (Dorland, 27th ed) Annotation: a mandibular abnorm; do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; consider also MALOCCLUSION, ANGLE CLASS II ID#: D012182Retrograde Degeneration
Definition: Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons. Annotation: ID#: D012183Retroperitoneal Fibrosis
Definition: A slowly progressive condition of unknown etiology, characterized by deposition of fibrous tissue in the retroperitoneal space compressing the ureters, great vessels, bile duct, and other structures. When associated with abdominal aortic aneurysm, it may be called chronic periaortitis or inflammatory perianeurysmal fibrosis. Annotation: ID#: D012185Retroperitoneal Neoplasms
Definition: Annotation: /blood supply /chem /second /secret /ultrastruct permitted; coord IM with histol type of neopl (IM) ID#: D012186Retropharyngeal Abscess
Definition: A soft tissue infection of the throat with entry usually by the pharynx but sometimes as an extension of a lateral neck infection resulting from a neck injury. The major risk is upper airway obstruction caused by pharyngeal swelling. (Daniel R. Masys, from a written communication) Annotation: for coord read note on ABSCESS ID#: D017703Retropneumoperitoneum
Definition: Pathological or accidental introduction of air into the retroperitoneal space. Annotation: note category: disease only; for diagnostic retropneumoperitoneum: index under RETROPERITONEAL SPACE /radiogr (IM) + PNEUMORADIOGRAPHY (NIM) ID#: D012188Retroviridae Infections
Definition: Virus diseases caused by the RETROVIRIDAE. Annotation: GEN or unspecified; prefer specifics ID#: D012192Rett Syndrome
Definition: An inherited disorder that is associated with X-linked transmission and may be lethal in utero to hemizygous males. Clinically, birth and development in affected females is normal until the age of 6-25 months, when progressive loss of voluntary control of hand movements and communication skills, ataxia, stereotypic hand movements, seizures, autistic behavior, intermittent hyperventilation, and hyperammonemia appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199) Annotation: ID#: D015518Reye Syndrome
Definition: An acute, potentially fatal metabolic disease seen primarily in children and characterized clinically by vomiting, hypoglycemia, and confusion, which may progress to coma. Pathologic features include cerebral edema and fatty infiltration of the liver and other organs. (From Adams et al., Principles of Neurology, 6th ed, p1120) Annotation: ID#: D012202Rhabditida Infections
Definition: Infections with nematodes of the order RHABDITIDA. Annotation: nematode infect ID#: D017196Rhabdoid Tumor
Definition: A rare but highly lethal childhood tumor found almost exclusively in infants. Histopathologically, it resembles RHABDOMYOSARCOMA but the tumor cells are not of myogenic origin. Although it arises primarily in the kidney, it may be found in other parts of the body. The rhabdoid cytomorphology is believed to be the expression of a very primitive malignant cell. (From Holland et al., Cancer Medicine, 3d ed, p2210) Annotation: /blood supply /chem /second /secret /ultrastruct permitted ID#: D018335Rhabdomyolysis
Definition: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. Annotation: "necrosis or disintegration of skeletal muscle often followed by myoglobinuria": do not index under MYOGLOBINURIA unless this is particularly discussed & then probably NIM ID#: D012206Rhabdomyoma
Definition: A benign tumor derived from striated muscle. It is extremely rare, generally occurring in the tongue, neck muscles, larynx, uvula, nasal cavity, axilla, vulva, and heart. These tumors are treated by simple excision. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1354) Annotation: /blood supply /chem /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM) ID#: D012207Rhabdomyosarcoma
Definition: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9) Annotation: GEN; prefer specifics; /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM) ID#: D012208Rhabdomyosarcoma, Alveolar
Definition: A form of RHABDOMYOSARCOMA occurring mainly in adolescents and young adults, affecting muscles of the extremities, trunk, orbital region, etc. It is extremely malignant, metastasizing widely at an early stage. Few cures have been achieved and the prognosis is poor. "Alveolar" refers to its microscopic appearance simulating the cells of the respiratory alveolus. (Holland et al., Cancer Medicine, 3d ed, p2188) Annotation: "alveolar" has nothing to do with pulm alveoli: it refers to sac-like pathol of musc affected; /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM) ID#: D018232Rhabdomyosarcoma, Embryonal
Definition: A form of RHABDOMYOSARCOMA arising primarily in the head and neck, especially the orbit, of children below the age of 10. The cells are smaller than those of other rhabdomyosarcomas and are of two basic cell types: spindle cells and round cells. This cancer is highly sensitive to chemotherapy and has a high cure rate with multi-modality therapy. (From Holland et al., Cancer Medicine, 3d ed, p2188) Annotation: /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM) ID#: D018233Rhabdoviridae Infections
Definition: Virus diseases caused by RHABDOVIRIDAE. Important infections include RABIES; EPHEMERAL FEVER; and vesicular stomatitis. Annotation: GEN or unspecified; prefer specifics ID#: D018353Rheumatic Diseases
Definition: Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement. Annotation: do not confuse with the specialty RHEUMATOLOGY; /drug ther: consider also ANTIRHEUMATIC AGENTS ID#: D012216Rheumatic Fever
Definition: A febrile disease occurring as a delayed sequela of infections with group A hemolytic streptococci and characterized by multiple focal inflammatory lesions of the connective tissue structures, especially of the heart, blood vessels, and joints (polyarthritis), and by the presence of Aschoff bodies in the myocardium and skin. (Dorland, 27th ed) Annotation: Strep infect; rheum fever with heart dis, unspecified or specific = RHEUMATIC HEART DISEASE (IM) + the specific heart dis (IM or NIM), but not HEART DISEASES ID#: D012213Rheumatic Heart Disease
Definition: The most important manifestation of and sequel to rheumatic fever, i.e., any cardiac involvement in rheumatic fever. (Dorland, 27th ed) Annotation: most important manifest of rheum fever; coord IM with specific dis of the heart (myocardium or valves) (IM or NIM) ID#: D012214Rheumatic Nodule
Definition: A small round or oval, mostly subcutaneous nodule made up chiefly of a mass of Aschoff bodies and seen in cases of rheumatic fever. It is differentiated from the RHEUMATOID NODULE which appears in rheumatoid arthritis, most frequently over bony prominences. (From Dorland, 27th ed) Annotation: in rheum fever; do not confuse with RHEUMATOID NODULE in rheum arthritis ID#: D012215Rheumatoid Nodule
Definition: Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes. Annotation: in rheum arthritis; do not confuse with RHEUMATIC NODULE in rheum fever ID#: D012218Rhinitis
Definition: Inflammation of the mucous membrane of the nose. Annotation: inflamm of nasal mucosa; GEN or unspecified; prefer specifics ID#: D012220Rhinitis, Allergic, Perennial
Definition: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc. Annotation: note X ref: do not confuse with RHINITIS, ALLERGIC, SEASONAL see HAY FEVER ID#: D012221Rhinitis, Atrophic
Definition: A chronic form of rhinitis marked by wasting of the mucous membrane and the glands. It is usually associated with crusting and foul-smelling discharges. Annotation: ID#: D012222Rhinitis, Vasomotor
Definition: A form of rhinitis brought about by changes in vascular tone and permeability. The etiology is obscure. Annotation: do not confuse with other RHINITIS headings; do not make diagnoses: use word of text ID#: D012223Rhinophyma
Definition: A manifestation of severe ACNE ROSACEA resulting in significant enlargement of the nose and occurring primarily in men. It is caused by hypertrophy of the sebaceous glands and surrounding connective tissue. The nose is reddened and marked with numerous telangiectasias. Annotation: enlargement of nose in severe acne rosacea ID#: D012224Rhinoscleroma
Definition: A granulomatous disease affecting the nose and nasopharynx, usually ascribed to KLEBSIELLA RHINOSCLEROMATIS. It occurs in Egypt, eastern Europe, and Central and South America. Annotation: ID#: D012226Rhinosporidiosis
Definition: Annotation: ID#: D012227Rib Fractures
Definition: Annotation: ID#: D012253Riboflavin Deficiency
Definition: A dietary deficiency of riboflavin causing a syndrome chiefly marked by cheilitis, angular stomatitis, glossitis associated with a purplish red or magenta-colored tongue that may show fissures, corneal vascularization, dyssebacia, and anemia. (Dorland, 27th ed) Annotation: a vitamin B defic ID#: D012257Rickets
Definition: A condition caused by deficiency of VITAMIN D, especially in infancy and childhood, with disturbance of normal ossification. The disease is marked by bending and distortion of the bones under muscular action, by the formation of nodular enlargements on the ends and sides of the bones, by delayed closure of the fontanels, pain in the muscles, and sweating of the head. Vitamin D and sunlight together with an adequate diet are curative, provided that the parathyroid glands are functioning properly. (Dorland, 27th ed) Annotation: consider also VITAMIN D DEFICIENCY & note next entry ID#: D012279Rickettsia Infections
Definition: Infections by the genus RICKETTSIA. Annotation: gram-neg bact infect; GEN or unspecified; prefer specific infection as shown at the various RICKETTSIA species; infection by genus RICKETTSIA: do not confuse with RICKETTSIACEAE INFECTIONS ("infections with rickettsias of the Family RICKETTSIACEAE"); Rickettsia conorii infection = BOUTONNEUSE FEVER; Rickettsia quintana infection = TRENCH FEVER ID#: D012282Rickettsiaceae Infections
Definition: Infections with bacteria of the family RICKETTSIACEAE. Annotation: gram-neg bact "infections with rickettsias of the family RICKETTSIACEAE": do not confuse with RICKETTSIA INFECTIONS (infection by genus RICKETTSIA) ID#: D012288Rickettsiales Infections
Definition: Infections with bacteria of the order RICKETTSIALES. Annotation: infect with gram-neg bact of order RICKETTSIALES: do not confuse with RICKETTSIACEAE INFECTIONS (family) or RICKETTSIA INFECTIONS (genus); GEN: avoid; prefer specifics; DF: RICKETTSIALES INFECT ID#: D016872Rift Valley Fever
Definition: A febrile disease resembling dengue. It is caused by a mosquito-borne arbovirus. Annotation: a hemorrhagic fever caused by a bunyavirus; in man or animal; in animal do not use /vet but check tag ANIMAL ID#: D012295Rigor Mortis
Definition: Muscular rigidity which develops in the cadaver usually from 4 to 10 hours after death and lasts 3 or 4 days. Annotation: ID#: D012298Rinderpest
Definition: A viral disease of cloven-hoofed animals caused by MORBILLIVIRUS. It may be acute, subacute, or chronic with the major lesions characterized by inflammation and ulceration of the entire digestive tract. Annotation: ID#: D012301RNA Virus Infections
Definition: Annotation: GEN or unspecified; prefer specifics; DF: RNA VIRUS INFECT ID#: D012327Rocky Mountain Spotted Fever
Definition: An acute febrile illness caused by RICKETTSIA RICKETTSII. It is transmitted to humans by bites of infected ticks and occurs only in North and South America. Characteristics include a sudden onset with headache and chills and fever lasting about two to three weeks. A cutaneous rash commonly appears on the extremities and trunk about the fourth day of illness. Annotation: caused by Rickettsia rickettsii; for X ref, in titles & translations use diacrit: São Paulo ID#: D012373Rodent Diseases
Definition: Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs). Annotation: IM GEN or unspecified; coord IM with specific dis /vet (IM) or specific rodent dis (IM); coord IM with specific rodent (IM); don't forget also RODENTIA (NIM) & check tag ANIMAL; DF: RODENT DIS ID#: D012376Romano-Ward Syndrome
Definition: An autosomal dominant LONG QT SYNDROME, without deafness. Annotation: ID#: D029597Root Caries
Definition: Dental caries involving the tooth root, cementum, or cervical area of the tooth. Annotation: caries of root, cementum or cervical portion of tooth ID#: D017213Roseolovirus Infections
Definition: Infection with ROSEOLOVIRUS, the most common in humans being EXANTHEMA SUBITUM, a benign disease of infants and young children. Annotation: caused by a genus of the family Herpesviridae ID#: D019349Rotavirus Infections
Definition: Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice. Annotation: caused by a reovirus ID#: D012400Rubella
Definition: An acute, usually benign, infectious disease caused by the RUBELLA VIRUS and most often affecting children and nonimmune young adults, in which the virus enters the respiratory tract via droplet nuclei and spreads to the lymphatic system. (From Dorland, 27th edition) Annotation: caused by a rubivirus, RUBELLA VIRUS: do not confuse with RUBULAVIRUS, a paramyxovirus; do not confuse with RUBEOLA see MEASLES; French for rubella = rubéole, Ital for rubella = rubeola, Span for rubella = rubéola or roséola epidemica; /congen: consider also RUBELLA SYNDROME, CONGENITAL ID#: D012409Rubella Syndrome, Congenital
Definition: Transplacental infection of the fetus with rubella usually in the first trimester of pregnancy, as a consequence of maternal infection, resulting in various developmental abnormalities in the newborn infant. They include cardiac and ocular lesions, deafness, microcephaly, mental retardation, and generalized growth retardation. (From Dorland, 27th ed) Annotation: caused by a rubivirus; do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; restrict to syndrome: see MeSH definition; otherwise RUBELLA /congen permitted ID#: D012410Rubinstein-Taybi Syndrome
Definition: A chromosomal disorder characterized by MENTAL RETARDATION, broad thumbs, webbing of fingers and toes, beaked nose, short upper lip, pouting lower lip, agenesis of corpus callosum, large foramen magnum, keloid formation, pulmonary stenosis, vertebral anomalies, chest wall anomalies, sleep apnea, and megacolon. The disease has an autosomal dominant pattern of inheritance and is associated with deletions of the short arm of chromosome 16 (16p13.3). Annotation: ID#: D012415Rubivirus Infections
Definition: Virus diseases caused by the RUBIVIRUS genus, of the family TOGAVIRIDAE. Annotation: caused by a togavirus; GEN or unspecified; prefer specifics ID#: D018355Rubulavirus Infections
Definition: Infections with viruses of the genus RUBULAVIRUS, family PARAMYXOVIRIDAE. Annotation: GEN or unspecified; prefer specifics; do not confuse with RUBELLA VIRUS infections ( = RUBELLA) ID#: D019351Rupture
Definition: Forcible or traumatic tear or break of an organ or other soft part of the body. Annotation: traumatic only: differentiate from RUPTURE, SPONTANEOUS; never IM: coord NIM with probably organ /inj (IM) or precoord inj term (IM) ID#: D012421Rupture, Spontaneous
Definition: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force. Annotation: includes spontan rupt unexplained or as a result of dis: differentiate from RUPTURE, traumatic only; never IM: coord NIM with organ/diseases term (IM) ID#: D012422